Bitiron T3 and T4 Mix
Bitiron T3 and T4 Mix 12.5 mcg / 50 mcg
Bitiron is a thyroid hormone replacement product generated from synthetic sources. It is made up of a 4 to 1 weight ratio of Levothyroxine sodium (Thyroxine, T4) and Liothyronine Sodium (Triiodothyronine, T3). Bitiron was created when it was thought that direct thyroidal secretion was the only way to keep serum levels of T4 and T3 stable. It is now known that the thyroid gland secretes approximately ten times more T4 than T3, and that deiodination of T4 in peripheral tissues accounts for 80 percent of blood T3. In most patients, Levothyroxine alone is sufficient to maintain serum T4 and T3 levels, and combination hormone replacement treatment provides no therapeutic benefit.
Thyroid hormone medicines are either natural or synthetic preparations that contain T4 or T3 or both. The human thyroid gland produces T4 and T3 by iodinating and coupling the amino acid tyrosine. Bitiron is a 4:1 weight-based synthetic combination of T4 and T3. These hormones increase the amount of oxygen consumed by most tissues in the body, as well as the basal metabolic rate and carbohydrate, lipid, and protein metabolism. As a result, they have a profound effect on every organ system in the body and are especially important in the development of the central nervous system.
The hormones, T4 and T3, are tyrosine-based hormones produced by the thyroid gland. Iodine is an important component in their synthesis. The major secreted form of thyroid hormone is T4. T4 is converted T3, the more active thyroid hormone, by deiodinases in peripheral tissues. T3 acts in the body to increase basal metabolic rate, alter protein synthesis and increase the body's sensitivity to catecholamines (such as adrenaline). Thyroid hormones are essential for proper development and differentiation of all cells of the human body. T4 and T3 regulate protein, fat and carbohydrate metabolism to varying extents. The most pronounced effect of the hormones is in altering how human cells use energetic compounds. The thyroid hormone derivatives bind to the thyroid hormone receptors initially to initiate their downstream effects.
T4 and T3 hormones are tyrosine-based hormones generated by the thyroid gland. Iodine plays an important role in their synthesis. T4 is the most commonly released type of thyroid hormone. Deiodinases in peripheral tissues convert T4 to T3, the more active thyroid hormone. T3 increases the body's baseline metabolic rate, alters protein synthesis, and increases sensitivity to catecholamines (such as adrenaline). Thyroid hormones are required for the correct development and differentiation of all human body cells. To differing degrees, T4 and T3 regulate protein, lipid, and carbohydrate metabolism.
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