Eltroxin 50 mcg
Eltroxin 100 mcg
Eltroxin comprises the synthetic thyroid hormone Levothyroxine (L-thyroxine); the levogyrate isomer of thyroxine (T4). Eltroxin works in the same way as the thyroid gland's natural thyroid hormone, thyroxine. It enters the bodily cells after biotransformation into liothyronine (in the liver and kidneys) and has regulatory effects on development, tissue growth, and metabolism. The mechanisms of metabolic impacts include receptor binding to the genome, changes in mitochondrial oxidative metabolism, and regulation of the flow of substrates and cations inside and outside the cells.
Eltroxin stimulates growth and development, raises oxygen demand in tissues, stimulates protein, lipid, and carbohydrate metabolism, and boosts the functional activity of the circulatory and neurological systems in medium doses. Eltroxin decreases the generation of thyrotropin-releasing hormone of the hypothalamus (TTRG) and pituitary thyroid stimulating hormone (PTSH) in large doses (TSH).
Eltroxin is prescribed on an individual basis based on the indications, functional state of the thyroid gland, thyroid gland size, age, weight, and cardiovascular system status. Eltroxin is typically taken once daily, on an empty stomach, 30 minutes before meals, by swallowing tablets with a small amount of water without chewing.
Individual intolerance (including a history of hypersensitivity to levothyroxine), untreated thyrotoxicosis (hyperthyroidism) of any origin, severe coronary insufficiency, acute myocardial infarction, angina pectoris, expressed atherosclerosis, acute myocarditis, severe arrhythmias, severe congestive heart failure, severe hypertension, uncontrolled adrenal insufficiency, untreated Addison' (over 65). The only absolute contraindication for replacement treatment is hypersensitivity to levothyroxine.
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